A yellow fever vaccination certificate is required for travellers arriving from countries with risk of yellow fever transmission, from Eritrea, Sao Tome and Principe, Somalia, Tanzania, Zambia, and for travellers having transited more than 12 hours through the airport of a country with risk of yellow fever transmission.
South Africa is otherwise a low risk area, and Yellow fever vaccination is not otherwise recommended.
Malaria: Cape Town and the Western Cape Province are considered safe, and visitors to these areas do not require Malaria prophylaxis.
Malaria risk due predominantly to P. falciparum exists throughout the year in the low?altitude areas of Mpumalanga Province (including the Kruger National Park), Limpopo Province and north?eastern KwaZulu?Natal. Should you be travelling to these areas, the use of prophylaxis is strongly recommended.